369 research outputs found

    WebDAVA: An Administrator-Free Approach To Web File-Sharing

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    Collaboration over the Internet depends on the ability of the members of a group to exchange data in a secure yet unobtrusive manner. WebDAVA is a system that allows the users to define their own access-control policies to network resources that they control, enabling secure data sharing within the enterprise. Our design allows users to selectively give fine-grain access to their resources without involving their system administrators. We accomplish this by using authorization credentials that define the users' privileges. Our prototype implements a file-sharing service, where users maintain sensitive-information folders and can allow others to access parts of these. Clients interact with the server over HTTP via a Java applet that transparently handles credential management. This mechanism allows users to share information with users not a priori known to the system, enabling administrator-free management

    Ultra-Low-Power Superconductor Logic

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    We have developed a new superconducting digital technology, Reciprocal Quantum Logic, that uses AC power carried on a transmission line, which also serves as a clock. Using simple experiments we have demonstrated zero static power dissipation, thermally limited dynamic power dissipation, high clock stability, high operating margins and low BER. These features indicate that the technology is scalable to far more complex circuits at a significant level of integration. On the system level, Reciprocal Quantum Logic combines the high speed and low-power signal levels of Single-Flux- Quantum signals with the design methodology of CMOS, including low static power dissipation, low latency combinational logic, and efficient device count.Comment: 7 pages, 5 figure

    LAI-Net: Local-Ancestry Inference with Neural Networks

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    Local-ancestry inference (LAI), also referred to as ancestry deconvolution, provides high-resolution ancestry estimation along the human genome. In both research and industry, LAI is emerging as a critical step in DNA sequence analysis with applications extending from polygenic risk scores (used to predict traits in embryos and disease risk in adults) to genome-wide association studies, and from pharmacogenomics to inference of human population history. While many LAI methods have been developed, advances in computing hardware (GPUs) combined with machine learning techniques, such as neural networks, are enabling the development of new methods that are fast, robust and easily shared and stored. In this paper we develop the first neural network based LAI method, named LAI-Net, providing competitive accuracy with state-of-the-art methods and robustness to missing or noisy data, while having a small number of layers

    BotArtist: Twitter bot detection Machine Learning model based on Twitter suspension

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    Twitter as one of the most popular social networks, offers a means for communication and online discourse, which unfortunately has been the target of bots and fake accounts, leading to the manipulation and spreading of false information. Towards this end, we gather a challenging, multilingual dataset of social discourse on Twitter, originating from 9M users regarding the recent Russo-Ukrainian war, in order to detect the bot accounts and the conversation involving them. We collect the ground truth for our dataset through the Twitter API suspended accounts collection, containing approximately 343K of bot accounts and 8M of normal users. Additionally, we use a dataset provided by Botometer-V3 with 1,777 Varol, 483 German accounts, and 1,321 US accounts. Besides the publicly available datasets, we also manage to collect 2 independent datasets around popular discussion topics of the 2022 energy crisis and the 2022 conspiracy discussions. Both of the datasets were labeled according to the Twitter suspension mechanism. We build a novel ML model for bot detection using the state-of-the-art XGBoost model. We combine the model with a high volume of labeled tweets according to the Twitter suspension mechanism ground truth. This requires a limited set of profile features allowing labeling of the dataset in different time periods from the collection, as it is independent of the Twitter API. In comparison with Botometer our methodology achieves an average 11% higher ROC-AUC score over two real-case scenario datasets

    SALAI-Net: species-agnostic local ancestry inference network

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    Availability and implementation: We provide an open source implementation and links to publicly available data at github.com/AI-sandbox/SALAI-Net. Data is publicly available as follows: https://www.internationalgenome.org (1000 Genomes), https://www.simonsfoundation.org/simons-genome-diversity-project (Simons Genome Diversity Project), https://www.sanger.ac.uk/resources/downloads/human/hapmap3.html (HapMap), ftp://ngs.sanger.ac.uk/production/hgdp/hgdp_wgs.20190516 (Human Genome Diversity Project) and https://www.ncbi.nlm.nih.gov/bioproject/PRJNA448733 (Canid genomes).Local ancestry inference (LAI) is the high resolution prediction of ancestry labels along a DNA sequence. LAI is important in the study of human history and migrations, and it is beginning to play a role in precision medicine applications including ancestry-adjusted genome-wide association studies (GWASs) and polygenic risk scores (PRSs). Existing LAI models do not generalize well between species, chromosomes or even ancestry groups, requiring re-training for each different setting. Furthermore, such methods can lack interpretability, which is an important element in each of these applications. We present SALAI-Net, a portable statistical LAI method that can be applied on any set of species and ancestries (species-agnostic), requiring only haplotype data and no other biological parameters. Inspired by identity by descent methods, SALAI-Net estimates population labels for each segment of DNA by performing a reference matching approach, which leads to an interpretable and fast technique. We benchmark our models on whole-genome data of humans and we test these models’ ability to generalize to dog breeds when trained on human data. SALAI-Net outperforms previous methods in terms of balanced accuracy, while generalizing between different settings, species and datasets. Moreover, it is up to two orders of magnitude faster and uses considerably less RAM memory than competing methods.This paper was published as part of a special issue financially supported by ECCB2022. Some of the computing for this project was performed on the Sherlock cluster at Stanford University. We would like to thank Stanford University and the Stanford Research Computing Center for providing computational resources and support that contributed to these research results. A.G.I. and D.M.M. received support from NIH under award R01HG010140. Conflict of Interest: AGI is a co-founder of Galatea Bio Inc.Peer ReviewedObjectius de Desenvolupament Sostenible::3 - Salut i BenestarObjectius de Desenvolupament Sostenible::3 - Salut i Benestar::3.4 - Per a 2030, reduir en un terç la mortalitat prematura per malalties no transmissibles, mitjançant la prevenció i el tractament, i promoure la salut mental i el benestarPostprint (published version

    Discovery and classification of Twitter bots

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    A very large number of people use Online Social Networks daily. Such platforms thus become attractive targets for agents that seek to gain access to the attention of large audiences, and influence perceptions or opinions. Botnets, collections of automated accounts controlled by a single agent, are a common mechanism for exerting maximum influence. Botnets may be used to better infiltrate the social graph over time and to create an illusion of community behavior, amplifying their message and increasing persuasion. This paper investigates Twitter botnets, their behavior, their interaction with user communities and their evolution over time. We analyzed a dense crawl of a subset of Twitter traffic, amounting to nearly all interactions by Greek-speaking Twitter users for a period of 36 months. We detected over a million events where seemingly unrelated accounts tweeted nearly identical content at nearly the same time. We filtered these concurrent content injection events and detected a set of 1,850 accounts that repeatedly exhibit this pattern of behavior, suggesting that they are fully or in part controlled and orchestrated by the same software. We found botnets that appear for brief intervals and disappear, as well as botnets that evolve and grow, spanning the duration of our dataset. We analyze statistical differences between bot accounts and human users, as well as botnet interaction with user communities and Twitter trending topics
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